ABSTRACT
Objective To explore the clinical application of located subcutaneous jugular vein inserted central catheter (LSJICC) in patients with malignant tumors. Methods The patients with malignant tumors treated in our hospital from January 2013 to December 2016 were enrolled and divided into the experimental group and the con-trol group according to the order of catheterization. Two groups were catheterized with LSJICC and PICC,respective-ly. Indwelling time of the catheter and incidence of complications were compared between two groups. The Kaplan-Meier survival curve was used to reflect the occurrence of CRBSIs in both groups,and the log-rank test was used to compare the results. The pathogenicity distribution of CRBSIs was analyzed and multivariate Cox regression analysis was performed. Results A total of 450 patients were enrolled in this study,including 228 patients in the experimental group and 222 patients in the control group. The average indwelling time of the catheter in the ex-perimental group(212.24 ± 79.80) was significantly longer than that in the control group(79.73 ± 34.86). The in-cidence of complications in the experimental group was significantly lower than that in the control group. The CRBSIs Kaplan-Meier survival curve of the experimental group was significantly better than that of the control group(P<0.01). The top three pathogens of CRBSIs were staphylococcus aureus,candida and klebsiella pneumoniae. Multivariate Cox regression analysis of CRBSIs showed that the site of catheter placement,the method of catheter placement and the type of tumor were independent risk factors for infection. Conclusion The incidence of compli-cations are significantly reduced with LSJICC,and indwelling time of the catheter is significantly prolonged,which is more in line with the actual needs of cancer patients undergoing chemotherapy.